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Optimization and characterization of spray-dried IgG formulations: a design of experiment approach

BACKGROUND: The purpose of the present study is to optimize a spray-dried formulation as a model antibody regarding stability and aerodynamic property for further aerosol therapy of this group of macromolecules. METHOD: A three-factor, three-level, Box-Behnken design was employed milligrams of Cyste...

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Detalles Bibliográficos
Autores principales:	Faghihi, Homa, Najafabadi, Abdolhosein Rouholamini, Vatanara, Alireza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678550/ https://www.ncbi.nlm.nih.gov/pubmed/29065930 http://dx.doi.org/10.1186/s40199-017-0187-8

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