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Hyperuricemia in type 2 diabetic model KK-A(y)/Ta mice: a potent animal model with positive correlation between insulin resistance and plasma high uric acid levels

OBJECTIVE: Hyperuricemia is recognized as a main cause of gout. Accumulating clinical evidence suggests that hyperuricemia is strongly associated with insulin resistance and abnormal glucose metabolism. However, there seem no proper animal models for investigating such associations. Ideal animal mod...

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Detalles Bibliográficos
Autores principales: Adachi, Shin-ichi, Yoshizawa, Fumiaki, Yagasaki, Kazumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678565/
https://www.ncbi.nlm.nih.gov/pubmed/29115981
http://dx.doi.org/10.1186/s13104-017-2897-x