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Hyperuricemia in type 2 diabetic model KK-A(y)/Ta mice: a potent animal model with positive correlation between insulin resistance and plasma high uric acid levels
OBJECTIVE: Hyperuricemia is recognized as a main cause of gout. Accumulating clinical evidence suggests that hyperuricemia is strongly associated with insulin resistance and abnormal glucose metabolism. However, there seem no proper animal models for investigating such associations. Ideal animal mod...
Autores principales: | Adachi, Shin-ichi, Yoshizawa, Fumiaki, Yagasaki, Kazumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678565/ https://www.ncbi.nlm.nih.gov/pubmed/29115981 http://dx.doi.org/10.1186/s13104-017-2897-x |
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