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A Drug Development Tool for Trial Enrichment in Patients With Autosomal Dominant Polycystic Kidney Disease

INTRODUCTION: Total kidney volume (TKV) is a promising imaging biomarker for tracking and predicting the natural history of patients with autosomal dominant polycystic kidney disease. METHODS: A drug development tool was developed by linking longitudinal TKV measurements to the probability of a 30%...

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Detalles Bibliográficos
Autores principales: Perrone, Ronald D., Mouksassi, Mohamad-Samer, Romero, Klaus, Czerwiec, Frank S., Chapman, Arlene B., Gitomer, Berenice Y., Torres, Vicente E., Miskulin, Dana C., Broadbent, Steve, Marier, Jean F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678607/
https://www.ncbi.nlm.nih.gov/pubmed/29142972
http://dx.doi.org/10.1016/j.ekir.2017.02.011