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Proximal Tubular Expression Patterns of Megalin and Cubilin in Proteinuric Nephropathies

INTRODUCTION: Receptor-mediated endocytosis is responsible for protein reabsorption in the proximal tubules. For albumin this process involves at least 2 interacting receptors, megalin and cubilin. Albumin is not usually present in the urine, indicating a highly efficient tubular reuptake under phys...

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Detalles Bibliográficos
Autores principales: Sun, Jia, Hultenby, Kjell, Axelsson, Jonas, Nordström, Johan, He, Bing, Wernerson, Annika, Lindström, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678615/
https://www.ncbi.nlm.nih.gov/pubmed/29142988
http://dx.doi.org/10.1016/j.ekir.2017.02.012