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Sclerostin─A Debutant on the Autosomal Dominant Polycystic Kidney Disease Scene?

INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease originating from a mutation in genes encoding polycystin 1 and 2. Recent evidence suggests that these polycystins mediate mechanosensation not only in the primary cilium of kidney cells but also in bone cells. Th...

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Detalles Bibliográficos
Autores principales: Jankowska, Magdalena, Haarhaus, Mathias, Qureshi, Abdul Rashid, Lindholm, Bengt, Evenepoel, Pieter, Stenvinkel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678633/
https://www.ncbi.nlm.nih.gov/pubmed/29142975
http://dx.doi.org/10.1016/j.ekir.2017.01.001