Profiling of Plasma Metabolites Suggests Altered Mitochondrial Fuel Usage and Remodeling of Sphingolipid Metabolism in Individuals With Type 2 Diabetes and Kidney Disease

INTRODUCTION: Pathophysiology of diabetic kidney disease (DKD) is incompletely understood. We aim to elucidate metabolic abnormalities associated with DKD in type 2 diabetes mellitus (T2DM) by targeted plasma metabolomics. METHODS: A total of 126 T2DM participants with early DKD (urinary albumin-to-...

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Detalles Bibliográficos
Autores principales: Liu, Jian-Jun, Ghosh, Sujoy, Kovalik, Jean-Paul, Ching, Jianhong, Choi, Hyung Won, Tavintharan, Subramaniam, Ong, Choon Nam, Sum, Chee Fang, Summers, Scott A., Tai, E. Shyong, Lim, Su Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678636/
https://www.ncbi.nlm.nih.gov/pubmed/29142974
http://dx.doi.org/10.1016/j.ekir.2016.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678636/
https://www.ncbi.nlm.nih.gov/pubmed/29142974
http://dx.doi.org/10.1016/j.ekir.2016.12.003

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