Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies

We recently demonstrated the effectiveness of blocking CD49d with anti-functional antibodies or small molecule inhibitors as a rational targeted approach to the treatment of acute leukemia in combination with chemotherapy. Antisense oligonucleotide promises to be no less specific than antibodies and...

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Detalles Bibliográficos
Autores principales: Duchartre, Yann, Bachl, Stefanie, Kim, Hye Na, Gang, Eun Ji, Lee, Solah, Liu, Hsiao-chuan, Shung, Kirk, Xu, Ruth, Kruse, Aaron, Tachas, George, Bonig, Halvard, Kim, Yong-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678723/
https://www.ncbi.nlm.nih.gov/pubmed/29117236
http://dx.doi.org/10.1371/journal.pone.0187684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678723/
https://www.ncbi.nlm.nih.gov/pubmed/29117236
http://dx.doi.org/10.1371/journal.pone.0187684

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