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Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies
We recently demonstrated the effectiveness of blocking CD49d with anti-functional antibodies or small molecule inhibitors as a rational targeted approach to the treatment of acute leukemia in combination with chemotherapy. Antisense oligonucleotide promises to be no less specific than antibodies and...
Autores principales: | Duchartre, Yann, Bachl, Stefanie, Kim, Hye Na, Gang, Eun Ji, Lee, Solah, Liu, Hsiao-chuan, Shung, Kirk, Xu, Ruth, Kruse, Aaron, Tachas, George, Bonig, Halvard, Kim, Yong-Mi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678723/ https://www.ncbi.nlm.nih.gov/pubmed/29117236 http://dx.doi.org/10.1371/journal.pone.0187684 |
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