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DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment

Multiple myeloma (MM) is a hematological malignancy resulting from the uncontrolled proliferation of antibody-producing plasma cells in the bone marrow. At diagnosis, independent plasma cell tumors are found throughout the skeleton. The recirculation of mutant plasma cells from the initial lesion an...

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Detalles Bibliográficos
Autores principales: Hewett, Duncan R., Vandyke, Kate, Lawrence, David M., Friend, Natasha, Noll, Jacqueline E., Geoghegan, Joel M., Croucher, Peter I., Zannettino, Andrew C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678743/
https://www.ncbi.nlm.nih.gov/pubmed/29091798
http://dx.doi.org/10.1016/j.neo.2017.09.004