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Toll-like receptor-4 differentially mediates intestinal and extra-intestinal immune responses upon multi-drug resistant Pseudomonas aeruginosa association of IL10(−/−) mice with chronic colitis

BACKGROUND: Infections with multi-drug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa (PA) have become a serious threat particularly in hospitalized patients with immunopathological co-morbidities. The well-balanced interplay between immune cells, pattern recognition recepto...

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Detalles Bibliográficos
Autores principales: Grunau, Anne, Escher, Ulrike, Kühl, Anja A., Bereswill, Stefan, Heimesaat, Markus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678768/
https://www.ncbi.nlm.nih.gov/pubmed/29151895
http://dx.doi.org/10.1186/s13099-017-0211-z