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Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza

BACKGROUND: A dry powder inhaled formulation is used for the anti-influenza drug laninamivir octanoate hydrate (laninamivir). Although two successive inhalations (puffs) are recommended to minimize residual amounts of active ingredients, previous reports suggest that pediatric patients with low peak...

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Detalles Bibliográficos
Autores principales: Murasaka, Toshiki, Ikemura, Kenji, Enokiya, Tomoyuki, Muraki, Yuichi, Ikemura, Mayumi, Terada, Koji, Iwamoto, Takuya, Okuda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678805/
https://www.ncbi.nlm.nih.gov/pubmed/29152321
http://dx.doi.org/10.1186/s40780-017-0094-7