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Development of a plasmid-based expression system in Clostridium thermocellum and its use to screen heterologous expression of bifunctional alcohol dehydrogenases (adhEs)

Clostridium thermocellum is a promising candidate for ethanol production from cellulosic biomass, but requires metabolic engineering to improve ethanol yield. A key gene in the ethanol production pathway is the bifunctional aldehyde and alcohol dehydrogenase, adhE. To explore the effects of overexpr...

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Detalles Bibliográficos
Autores principales: Hon, Shuen, Lanahan, Anthony A., Tian, Liang, Giannone, Richard J., Hettich, Robert L., Olson, Daniel G., Lynd, Lee R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678826/
https://www.ncbi.nlm.nih.gov/pubmed/29142822
http://dx.doi.org/10.1016/j.meteno.2016.04.001