Ethanol‐induced steatosis involves impairment of lipophagy, associated with reduced Dynamin2 activity

Lipid droplets (LDs), the organelles central to alcoholic steatosis, are broken down by lipophagy, a specialized form of autophagy. Here, we hypothesize that ethanol administration retards lipophagy by down‐regulating dynamin 2 (Dyn2), a protein that facilitates lysosome re‐formation, contributing t...

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Detalles Bibliográficos
Autores principales: Rasineni, Karuna, Donohue, Terrence M., Thomes, Paul G., Yang, Li, Tuma, Dean J., McNiven, Mark A., Casey, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678901/
https://www.ncbi.nlm.nih.gov/pubmed/29152606
http://dx.doi.org/10.1002/hep4.1063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678901/
https://www.ncbi.nlm.nih.gov/pubmed/29152606
http://dx.doi.org/10.1002/hep4.1063

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