Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate‐activated protein kinase‐related kinases and retinoid X receptor α

Ribavirin (RBV) has been widely used as an antiviral reagent, specifically for patients with chronic hepatitis C. We previously demonstrated that adenosine kinase, which monophosphorylates RBV into the metabolically active form, is a key determinant for RBV sensitivity against hepatitis C virus RNA...

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Detalles Bibliográficos
Autores principales: Satoh, Shinya, Mori, Kyoko, Onomura, Daichi, Ueda, Youki, Dansako, Hiromichi, Honda, Masao, Kaneko, Shuichi, Ikeda, Masanori, Kato, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678905/
https://www.ncbi.nlm.nih.gov/pubmed/29404478
http://dx.doi.org/10.1002/hep4.1065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678905/
https://www.ncbi.nlm.nih.gov/pubmed/29404478
http://dx.doi.org/10.1002/hep4.1065

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