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High‐mobility‐group protein 2 regulated by microRNA‐127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells

High‐mobility‐group protein 2 (HMGB2) expression is up‐regulated in human liver cancer; however, little is known about its regulatory function. Here, we establish HMGB2 as a new modulator of the pluripotency of mouse embryonic stem cells. Similar to octamer‐binding transcription factor 4 (OCT4) and...

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Detalles Bibliográficos
Autores principales: Zhao, Yulan, Yang, Zhihong, Wu, Jianguo, Wu, Raymond, Keshipeddy, Santosh K., Wright, Dennis, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678910/
https://www.ncbi.nlm.nih.gov/pubmed/29218329
http://dx.doi.org/10.1002/hep4.1086