Nicotinamide N‐methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes

Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload. We studied the effect of iron overload on the hepatic transcriptional and metabolomic...

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Detalles Bibliográficos
Autores principales: Koppe, Tiago, Patchen, Bonnie, Cheng, Aaron, Bhasin, Manoj, Vulpe, Chris, Schwartz, Robert E., Moreno‐Navarrete, Jose Maria, Fernandez‐Real, Jose Manuel, Pissios, Pavlos, Fraenkel, Paula G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678920/
https://www.ncbi.nlm.nih.gov/pubmed/29404495
http://dx.doi.org/10.1002/hep4.1083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678920/
https://www.ncbi.nlm.nih.gov/pubmed/29404495
http://dx.doi.org/10.1002/hep4.1083

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