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Asian Zika virus strains target CD14(+) blood monocytes and induce M2-skewed immunosuppression during pregnancy
Blood CD14(+) monocytes are the frontline immunomodulators categorized into classical, intermediate or non-classical subsets, subsequently differentiating into M1 pro- or M2 anti-inflammatory macrophages upon stimulation. While Zika virus (ZIKV) rapidly establishes viremia, the target cells and immu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678934/ https://www.ncbi.nlm.nih.gov/pubmed/28827581 http://dx.doi.org/10.1038/s41564-017-0016-3 |