Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging

Red-shifted bioluminescence reporters are desirable for biological imaging. We describe the development of red-shifted luciferins based on synthetic coelenterazine analogs and corresponding mutants of NanoLuc that enable bright bioluminescence. One pair in particular shows superior sensitivity over...

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Detalles Bibliográficos
Autores principales: Yeh, Hsien-Wei, Karmach, Omran, Ji, Ao, Carter, David, Martins-Green, Manuela M., Ai, Hui-wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678970/
https://www.ncbi.nlm.nih.gov/pubmed/28869756
http://dx.doi.org/10.1038/nmeth.4400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678970/
https://www.ncbi.nlm.nih.gov/pubmed/28869756
http://dx.doi.org/10.1038/nmeth.4400

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