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Dynamic regulation of T Follicular Regulatory cell responses by interleukin 2 during influenza infection

Interleukin 2 (IL-2) promotes Foxp3(+)-regulatory T (T(reg)) cell responses, but inhibits T follicular helper (T(FH)) cell development. However, it is not clear how IL-2 affects T follicular regulatory (T(FR)) cells, a cell type with properties of both T(reg) and T(FH) cells. Using an influenza infe...

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Detalles Bibliográficos
Autores principales: Botta, Davide, Fuller, Michael J., Marquez-Lago, Tatiana T., Bachus, Holly, Bradley, John. E., Weinmann, Amy S., Zajac, Allan. J., Randall, Troy D., Lund, Frances E., León, Beatriz, Ballesteros-Tato, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679073/
https://www.ncbi.nlm.nih.gov/pubmed/28892471
http://dx.doi.org/10.1038/ni.3837