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Direct interaction with 14–3-3γ promotes surface expression of Best1 channel in astrocyte

BACKGROUND: Bestrophin-1 (Best1) is a calcium-activated anion channel (CAAC) that is expressed broadly in mammalian tissues including the brain. We have previously reported that Best1 is expressed in hippocampal astrocytes at the distal peri-synaptic regions, called microdomains, right next to synap...

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Detalles Bibliográficos
Autores principales: Oh, Soo-Jin, Woo, Junsung, Lee, Young-Sun, Cho, Minhee, Kim, Eunju, Cho, Nam-Chul, Park, Jae-Yong, Pae, Ae Nim, Justin Lee, C., Hwang, Eun Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679146/
https://www.ncbi.nlm.nih.gov/pubmed/29121962
http://dx.doi.org/10.1186/s13041-017-0331-x