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Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease

BACKGROUND: In chronic obstructive pulmonary disease (COPD), weakness and muscle mass loss of the quadriceps muscle has been demonstrated to predict survival and mortality rates of patients. Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), as a member of the TNF superfamily, has r...

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Detalles Bibliográficos
Autores principales: Lu, Jun-Juan, Wang, Qing, Xie, Li Hua, Zhang, Qiang, Sun, Sheng Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679159/
https://www.ncbi.nlm.nih.gov/pubmed/29151827
http://dx.doi.org/10.1186/s12971-017-0148-5