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RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense
Many pathogens deliver virulence factors or effectors into host cells in order to evade host defenses and establish infection. Although such effector proteins disrupt critical cellular signaling pathways, they also trigger specific antipathogen responses, a process termed “effector-triggered immunit...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679171/ https://www.ncbi.nlm.nih.gov/pubmed/28855241 http://dx.doi.org/10.1084/jem.20170347 |