RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

Many pathogens deliver virulence factors or effectors into host cells in order to evade host defenses and establish infection. Although such effector proteins disrupt critical cellular signaling pathways, they also trigger specific antipathogen responses, a process termed “effector-triggered immunit...

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Detalles Bibliográficos
Autores principales: Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679171/
https://www.ncbi.nlm.nih.gov/pubmed/28855241
http://dx.doi.org/10.1084/jem.20170347

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