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STING-associated vasculopathy develops independently of IRF3 in mice

Patients with stimulator of interferon genes (STING)–associated vasculopathy with onset in infancy (SAVI) develop systemic inflammation characterized by vasculopathy, interstitial lung disease, ulcerative skin lesions, and premature death. Autosomal dominant mutations in STING are thought to trigger...

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Detalles Bibliográficos
Autores principales: Warner, James D., Irizarry-Caro, Ricardo A., Bennion, Brock G., Ai, Teresa L., Smith, Amber M., Miner, Cathrine A., Sakai, Tomomi, Gonugunta, Vijay K., Wu, Jianjun, Platt, Derek J., Yan, Nan, Miner, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679177/
https://www.ncbi.nlm.nih.gov/pubmed/28951494
http://dx.doi.org/10.1084/jem.20171351