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STING-associated vasculopathy develops independently of IRF3 in mice
Patients with stimulator of interferon genes (STING)–associated vasculopathy with onset in infancy (SAVI) develop systemic inflammation characterized by vasculopathy, interstitial lung disease, ulcerative skin lesions, and premature death. Autosomal dominant mutations in STING are thought to trigger...
Autores principales: | Warner, James D., Irizarry-Caro, Ricardo A., Bennion, Brock G., Ai, Teresa L., Smith, Amber M., Miner, Cathrine A., Sakai, Tomomi, Gonugunta, Vijay K., Wu, Jianjun, Platt, Derek J., Yan, Nan, Miner, Jonathan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679177/ https://www.ncbi.nlm.nih.gov/pubmed/28951494 http://dx.doi.org/10.1084/jem.20171351 |
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