B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

Recent studies have identified critical roles for B cells in triggering autoimmune germinal centers (GCs) in systemic lupus erythematosus (SLE) and other disorders. The mechanisms whereby B cells facilitate loss of T cell tolerance, however, remain incompletely defined. Activated B cells produce int...

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Detalles Bibliográficos
Autores principales: Arkatkar, Tanvi, Du, Samuel W., Jacobs, Holly M., Dam, Elizabeth M., Hou, Baidong, Buckner, Jane H., Rawlings, David J., Jackson, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679179/
https://www.ncbi.nlm.nih.gov/pubmed/28899868
http://dx.doi.org/10.1084/jem.20170580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679179/
https://www.ncbi.nlm.nih.gov/pubmed/28899868
http://dx.doi.org/10.1084/jem.20170580

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