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Effects of hypoglycemia on myocardial susceptibility to ischemia–reperfusion injury and preconditioning in hearts from rats with and without type 2 diabetes

BACKGROUND: Hypoglycemia is associated with increased mortality rate in patients with diabetes. The underlying mechanisms may involve reduced myocardial tolerance to ischemia and reperfusion (IR) or reduced capacity for ischemic preconditioning (IPC). As IPC is associated with increased myocardial g...

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Detalles Bibliográficos
Autores principales: Pælestik, Kim B., Jespersen, Nichlas R., Jensen, Rebekka V., Johnsen, Jacob, Bøtker, Hans Erik, Kristiansen, Steen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679182/
https://www.ncbi.nlm.nih.gov/pubmed/29121919
http://dx.doi.org/10.1186/s12933-017-0628-1