Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex

Quantitative measurement of transcription rates in live cells is important for revealing mechanisms of transcriptional regulation. This is particularly challenging for measuring the activity of RNA polymerase III (Pol III), which transcribes growth-promoting small RNAs. To address this, we developed...

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Detalles Bibliográficos
Autores principales: Song, Wenjiao, Filonov, Grigory S., Kim, Hyaeyeong, Hirsch, Markus, Li, Xing, Moon, Jared D., Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679246/
https://www.ncbi.nlm.nih.gov/pubmed/28945233
http://dx.doi.org/10.1038/nchembio.2477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679246/
https://www.ncbi.nlm.nih.gov/pubmed/28945233
http://dx.doi.org/10.1038/nchembio.2477

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