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Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex
Quantitative measurement of transcription rates in live cells is important for revealing mechanisms of transcriptional regulation. This is particularly challenging for measuring the activity of RNA polymerase III (Pol III), which transcribes growth-promoting small RNAs. To address this, we developed...
Autores principales: | Song, Wenjiao, Filonov, Grigory S., Kim, Hyaeyeong, Hirsch, Markus, Li, Xing, Moon, Jared D., Jaffrey, Samie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679246/ https://www.ncbi.nlm.nih.gov/pubmed/28945233 http://dx.doi.org/10.1038/nchembio.2477 |
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