Endothelial α6β4 integrin protects during experimental autoimmune encephalomyelitis-induced neuroinflammation by maintaining vascular integrity and tight junction protein expression

BACKGROUND: Extracellular matrix (ECM) proteins play critical functions regulating vascular formation and function. Laminin is a major component of the vascular basal lamina, and transgenic mice deficient in astrocyte or pericyte laminin show defective blood-brain barrier (BBB) integrity, indicating...

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Detalles Bibliográficos
Autores principales: Welser, Jennifer V., Halder, Sebok K., Kant, Ravi, Boroujerdi, Amin, Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679365/
https://www.ncbi.nlm.nih.gov/pubmed/29121970
http://dx.doi.org/10.1186/s12974-017-0987-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679365/
https://www.ncbi.nlm.nih.gov/pubmed/29121970
http://dx.doi.org/10.1186/s12974-017-0987-2

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