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Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing

BACKGROUND: Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d’origine nantais (RON) receptor is a single-pass transmembrane RTK aberrantly expressed in a number of cancers. Efforts to block deregulated RON signaling in tumors us...

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Detalles Bibliográficos
Autores principales: Krishnaswamy, Soundararajan, Mohammed, Abdul Khader, Tripathi, Gyanendra, Alokail, Majed S., Al-Daghri, Nasser M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679369/
https://www.ncbi.nlm.nih.gov/pubmed/29121914
http://dx.doi.org/10.1186/s12885-017-3747-x