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Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) structural protein Gag is necessary and sufficient to form viral particles. In addition to encoding the amino acid sequence for Gag, the underlying RNA sequence could encode cis-acting elements or nucleotide biases that are necessary for vi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679385/ https://www.ncbi.nlm.nih.gov/pubmed/29121951 http://dx.doi.org/10.1186/s12977-017-0374-1 |