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Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) structural protein Gag is necessary and sufficient to form viral particles. In addition to encoding the amino acid sequence for Gag, the underlying RNA sequence could encode cis-acting elements or nucleotide biases that are necessary for vi...

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Detalles Bibliográficos
Autores principales:	Antzin-Anduetza, Irati, Mahiet, Charlotte, Granger, Luke A., Odendall, Charlotte, Swanson, Chad M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679385/ https://www.ncbi.nlm.nih.gov/pubmed/29121951 http://dx.doi.org/10.1186/s12977-017-0374-1

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