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Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls

OBJECTIVE: To analyze longitudinal levels of CSF biomarkers in drug-naive patients with Parkinson disease (PD) and healthy controls (HC), examine the extent to which these biomarker changes relate to clinical measures of PD, and identify what may influence them. METHODS: CSF α-synuclein (α-syn), tot...

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Detalles Bibliográficos
Autores principales: Mollenhauer, Brit, Caspell-Garcia, Chelsea J., Coffey, Christopher S., Taylor, Peggy, Shaw, Leslie M., Trojanowski, John Q., Singleton, Andy, Frasier, Mark, Marek, Kenneth, Galasko, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679418/
https://www.ncbi.nlm.nih.gov/pubmed/29030452
http://dx.doi.org/10.1212/WNL.0000000000004609