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Sequence-based information-theoretic features for gene essentiality prediction

BACKGROUND: Identification of essential genes is not only useful for our understanding of the minimal gene set required for cellular life but also aids the identification of novel drug targets in pathogens. In this work, we present a simple and effective gene essentiality prediction method using inf...

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Detalles Bibliográficos
Autores principales: Nigatu, Dawit, Sobetzko, Patrick, Yousef, Malik, Henkel, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679510/
https://www.ncbi.nlm.nih.gov/pubmed/29121868
http://dx.doi.org/10.1186/s12859-017-1884-5