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Sequence-based information-theoretic features for gene essentiality prediction
BACKGROUND: Identification of essential genes is not only useful for our understanding of the minimal gene set required for cellular life but also aids the identification of novel drug targets in pathogens. In this work, we present a simple and effective gene essentiality prediction method using inf...
Autores principales: | Nigatu, Dawit, Sobetzko, Patrick, Yousef, Malik, Henkel, Werner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679510/ https://www.ncbi.nlm.nih.gov/pubmed/29121868 http://dx.doi.org/10.1186/s12859-017-1884-5 |
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