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Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

OBJECTIVE: In order to search for metabolic biomarkers of antihypertensive drug responsiveness, we measured >600 biochemicals in plasma samples of subjects participating in the GENRES Study. Hypertensive men received in a double-blind rotational fashion amlodipine, bisoprolol, hydrochlorothiazide...

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Detalles Bibliográficos
Autores principales: Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679533/
https://www.ncbi.nlm.nih.gov/pubmed/29121091
http://dx.doi.org/10.1371/journal.pone.0187729