Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase

Ligand of Numb protein X1 (LNX1) is an E3 ubiquitin ligase that contains a catalytic RING (Really Interesting New Gene) domain and four PDZ (PSD-95, DlgA, ZO-1) domains. LNX1 can ubiquitinate Numb, as well as a number of other ligands. However, the physiological relevance of these interactions in vi...

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Detalles Bibliográficos
Autores principales: Lenihan, Joan A., Saha, Orthis, Young, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679597/
https://www.ncbi.nlm.nih.gov/pubmed/29121065
http://dx.doi.org/10.1371/journal.pone.0187352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679597/
https://www.ncbi.nlm.nih.gov/pubmed/29121065
http://dx.doi.org/10.1371/journal.pone.0187352

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