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Functional evaluation of therapeutic response of HCC827 lung cancer to bevacizumab and erlotinib targeted therapy using dynamic contrast-enhanced and diffusion-weighted MRI

This study aimed to investigate the therapeutic responses of lung cancer mice models with adenocarcinoma HCC827 (gefitinib sensitive) and HCC827R (gefitinib resistant) to the epidermal growth factor receptor-tyrosine kinase inhibitor erlotinib alone and in combination with the anti-angiogenesis agen...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Fang, Yuan, Ang, Cho, Kuan-Hung, Lu, Yi-Chien, Kuo, Mark Yen-Ping, Chen, Jyh-Horng, Chang, Yeun-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679602/
https://www.ncbi.nlm.nih.gov/pubmed/29121075
http://dx.doi.org/10.1371/journal.pone.0187824