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CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies

Rapidly increasing number of therapeutic antibodies are being repurposed to imaging probes for noninvasive diagnosis, as well as monitoring during treatment or disease recurrence. Though antibody-based imaging involves tracer doses (~3 log lower than therapeutic doses), and immune responses are seve...

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Detalles Bibliográficos
Autores principales: Srinivasula, Sharat, Gabriel, Erin, Kim, Insook, DeGrange, Paula, St Claire, Alexis, Mallow, Candace, Donahue, Robert E., Paik, Chang, Lane, H. C., Di Mascio, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679608/
https://www.ncbi.nlm.nih.gov/pubmed/29121114
http://dx.doi.org/10.1371/journal.pone.0187912