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CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies
Rapidly increasing number of therapeutic antibodies are being repurposed to imaging probes for noninvasive diagnosis, as well as monitoring during treatment or disease recurrence. Though antibody-based imaging involves tracer doses (~3 log lower than therapeutic doses), and immune responses are seve...
Autores principales: | Srinivasula, Sharat, Gabriel, Erin, Kim, Insook, DeGrange, Paula, St Claire, Alexis, Mallow, Candace, Donahue, Robert E., Paik, Chang, Lane, H. C., Di Mascio, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679608/ https://www.ncbi.nlm.nih.gov/pubmed/29121114 http://dx.doi.org/10.1371/journal.pone.0187912 |
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