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Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage

Islet transplantation is a useful cell replacement therapy that can restore the glycometabolic function of severe diabetic patients. It is known that many transplanted islets failed to engraft, and thus, new approaches for overcoming graft loss that may improve the outcome of future clinical islet t...

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Detalles Bibliográficos
Autores principales: Sakata, Naoaki, Yamaguchi, Yohko, Chen, Yu, Shimoda, Masayuki, Yoshimatsu, Gumpei, Unno, Michiaki, Sumi, Shoichiro, Ohki, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679611/
https://www.ncbi.nlm.nih.gov/pubmed/29121094
http://dx.doi.org/10.1371/journal.pone.0187927