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Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage
Islet transplantation is a useful cell replacement therapy that can restore the glycometabolic function of severe diabetic patients. It is known that many transplanted islets failed to engraft, and thus, new approaches for overcoming graft loss that may improve the outcome of future clinical islet t...
Autores principales: | Sakata, Naoaki, Yamaguchi, Yohko, Chen, Yu, Shimoda, Masayuki, Yoshimatsu, Gumpei, Unno, Michiaki, Sumi, Shoichiro, Ohki, Rieko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679611/ https://www.ncbi.nlm.nih.gov/pubmed/29121094 http://dx.doi.org/10.1371/journal.pone.0187927 |
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