Metabolic regulation of GLP-1 and PC1/3 in pancreatic α-cell line

BACKGROUND AND AIMS: An intra-islet incretin system has been recently suggested to operate through modulation of the expression and activity of proconvertase 1/3 and 2 (PC1/3, PC2) in pancreatic alpha-cell accounting for local release of GLP-1. Little is known, whether this alpha-cell activity can b...

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Detalles Bibliográficos
Autores principales: Sancho, Veronica, Daniele, Giuseppe, Lucchesi, Daniela, Lupi, Roberto, Ciccarone, Annamaria, Penno, Giuseppe, Bianchi, Cristina, Dardano, Angela, Miccoli, Roberto, Del Prato, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679617/
https://www.ncbi.nlm.nih.gov/pubmed/29121068
http://dx.doi.org/10.1371/journal.pone.0187836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679617/
https://www.ncbi.nlm.nih.gov/pubmed/29121068
http://dx.doi.org/10.1371/journal.pone.0187836

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