Hypertrophic cardiomyopathy clinical phenotype is independent of gene mutation and mutation dosage

Over 1,500 gene mutations are known to cause hypertrophic cardiomyopathy (HCM). Previous studies suggest that cardiac β-myosin heavy chain (MYH7) gene mutations are commonly associated with a more severe phenotype, compared to cardiac myosin binding protein-C (MYBPC3) gene mutations with milder phen...

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Detalles Bibliográficos
Autores principales: Viswanathan, Shiv Kumar, Sanders, Heather K., McNamara, James W., Jagadeesan, Aravindakshan, Jahangir, Arshad, Tajik, A. Jamil, Sadayappan, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679632/
https://www.ncbi.nlm.nih.gov/pubmed/29121657
http://dx.doi.org/10.1371/journal.pone.0187948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679632/
https://www.ncbi.nlm.nih.gov/pubmed/29121657
http://dx.doi.org/10.1371/journal.pone.0187948

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