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Neuropathological and transcriptomic characteristics of the aged brain

As more people live longer, age-related neurodegenerative diseases are an increasingly important societal health issue. Treatments targeting specific pathologies such as amyloid beta in Alzheimer’s disease (AD) have not led to effective treatments, and there is increasing evidence of a disconnect be...

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Detalles Bibliográficos
Autores principales: Miller, Jeremy A, Guillozet-Bongaarts, Angela, Gibbons, Laura E, Postupna, Nadia, Renz, Anne, Beller, Allison E, Sunkin, Susan M, Ng, Lydia, Rose, Shannon E, Smith, Kimberly A, Szafer, Aaron, Barber, Chris, Bertagnolli, Darren, Bickley, Kristopher, Brouner, Krissy, Caldejon, Shiella, Chapin, Mike, Chua, Mindy L, Coleman, Natalie M, Cudaback, Eiron, Cuhaciyan, Christine, Dalley, Rachel A, Dee, Nick, Desta, Tsega, Dolbeare, Tim A, Dotson, Nadezhda I, Fisher, Michael, Gaudreault, Nathalie, Gee, Garrett, Gilbert, Terri L, Goldy, Jeff, Griffin, Fiona, Habel, Caroline, Haradon, Zeb, Hejazinia, Nika, Hellstern, Leanne L, Horvath, Steve, Howard, Kim, Howard, Robert, Johal, Justin, Jorstad, Nikolas L, Josephsen, Samuel R, Kuan, Chihchau L, Lai, Florence, Lee, Eric, Lee, Felix, Lemon, Tracy, Li, Xianwu, Marshall, Desiree A, Melchor, Jose, Mukherjee, Shubhabrata, Nyhus, Julie, Pendergraft, Julie, Potekhina, Lydia, Rha, Elizabeth Y, Rice, Samantha, Rosen, David, Sapru, Abharika, Schantz, Aimee, Shen, Elaine, Sherfield, Emily, Shi, Shu, Sodt, Andy J, Thatra, Nivretta, Tieu, Michael, Wilson, Angela M, Montine, Thomas J, Larson, Eric B, Bernard, Amy, Crane, Paul K, Ellenbogen, Richard G, Keene, C Dirk, Lein, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679757/
https://www.ncbi.nlm.nih.gov/pubmed/29120328
http://dx.doi.org/10.7554/eLife.31126