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Model-based local density sharpening of cryo-EM maps

Atomic models based on high-resolution density maps are the ultimate result of the cryo-EM structure determination process. Here, we introduce a general procedure for local sharpening of cryo-EM density maps based on prior knowledge of an atomic reference structure. The procedure optimizes contrast...

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Detalles Bibliográficos
Autores principales: Jakobi, Arjen J, Wilmanns, Matthias, Sachse, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679758/
https://www.ncbi.nlm.nih.gov/pubmed/29058676
http://dx.doi.org/10.7554/eLife.27131