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Genetic and pharmacological antagonism of NK(1) receptor prevents opiate abuse potential
Development of an efficacious, non-addicting analgesic has been challenging. Discovery of novel mechanisms underlying addiction may present a solution. Here, we target the neurokinin system, which is involved in both pain and addiction. Morphine exerts its rewarding actions, at least in part, by inh...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680162/ https://www.ncbi.nlm.nih.gov/pubmed/28485408 http://dx.doi.org/10.1038/mp.2017.102 |