Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathway

In order to ensure successful development, cells of the early mammalian embryo must differentiate to either trophectoderm (TE) or inner cell mass (ICM), followed by epiblast (EPI) or primitive endoderm (PE) specification within the ICM. Here, we deciphered the mechanism that assures the correct orde...

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Detalles Bibliográficos
Autores principales: Wigger, M., Kisielewska, K., Filimonow, K., Plusa, B., Maleszewski, M., Suwińska, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680175/
https://www.ncbi.nlm.nih.gov/pubmed/29123210
http://dx.doi.org/10.1038/s41598-017-15427-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680175/
https://www.ncbi.nlm.nih.gov/pubmed/29123210
http://dx.doi.org/10.1038/s41598-017-15427-0

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